When does the loss of any resource typically occur?

The loss of any resource typically occurs when someone fails to properly safeguard resources. Proper safeguarding involves implementing measures to protect resources from theft, damage, or improper usage. When these safeguards are not in place, vulnerabilities can arise, making it easier for resources to be lost, misallocated, or damaged. This action or inaction can often lead to a tangible loss that would not occur if the resources were adequately protected.

Regarding the other potential choices, while outdated resources can lead to inefficiencies or the eventual loss of relevance, it does not directly lead to loss in terms of theft or safety. Similarly, if resources are not used, they may become obsolete or expire but are not considered lost in the same context. Lastly, failing to perform inventory checks can result in discrepancies and may obscure losses, but does not inherently cause resource loss directly. Safeguarding remains the fundamental factor in maintaining resource integrity and preventing loss.