What MAJCOM performs depot-level maintenance of weapons system components?

The major command responsible for depot-level maintenance of weapons system components is Air Force Materiel Command (AFMC). This command oversees the overall maintenance, repair, and management of equipment needed for air operations, including aircraft armament systems. AFMC is tasked with ensuring that weapons systems are functional and reliable through extensive maintenance processes, which take place at dedicated depots. These facilities are equipped to handle the complex repairs and overhauls required for advanced military equipment.

In contrast, the other commands listed, such as Air Education and Training Command (AETC), Air Force Special Operations Command (AFSOC), and Air Combat Command (ACC), have distinct missions that do not primarily focus on depot-level maintenance. AETC is mainly involved in training and educating air personnel, AFSOC focuses on special operations forces, and ACC is responsible for preparing combat-ready forces. Thus, while they contribute to the operational readiness of the Air Force, they do not engage directly in the depot maintenance of weapons systems, making AFMC the correct answer.